Total Seduction 2

Or TS2 is an open world adult game. At the start of the game, you take a job as an intern in a lab and you end up field testing an experimental device called Chemical Augmentation Device (or CHAD). This sub-dermal implant can produce a wide array of various chemicals, hormones, pheromones and drugs to enhance your abilities. CHAD has it's own AI and it learns as time progress. Thus it can manufacture more complex chemicals as it improves itself, eventually granting you near supernatural abilities.

TS2 is an open world real time 3D game and a successor to Total Seduction 1. You control main character from isometric view with free camera rotation and zoom. All scenes are animated and controllable. The game has a main quest, but it is not time sensitive, so you are free to explore large in-game world, full of interesting characters and stories.

You can also play as a female or futa, either from the start of the game or transform at will later in the game, once you unlock required skills. Playing as female/futa will grant you new interactions, jobs and opportunities.